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Article

Clusterin expression can be modulated by changes in TCF1-mediated Wnt signaling

16 Jul 2007

Abstract excerpt

BACKGROUND: Clusterin (CLU) is an enigmatic molecule associated with various physiological processes and disease states. Different modes of cellular stress lead to increased CLU levels, and additionally numerous growth factors and cytokines affect the expression of the CLU gene. APC and c-MYC, both intimately linked to the Wnt signaling pathway have previously been shown to influence CLU levels, and we therefore...

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PMID: 17634137
DOI: 10.1186/1750-2187-2-6

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