Article
CLU and colon cancer. The dual face of CLU: from normal to malignant phenotype.
Advances in cancer research - 1 Jan 2009
Mazzarelli P, Pucci Sabina, Spagnoli L G
Abstract excerpt
The transition from normal to malignant phenotype implies the activation of some pathways that underlie the aberrant clone expansion. In some way, the conventional function of proteins involved in DNA repair, cell death/growth induction, vascularization, and metabolism is inhibited or shifted toward other pathways by soluble mediators that orchestrate such change depending on the microenvironment conditions. The...
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