Article
JAK2 as a molecular marker in myeloproliferative diseases.
Cardiovascular & hematological agents in medicinal chemistry - 1 Jul 2007
Mata R, Subirá D, García-Raso A, Llamas P
Abstract excerpt
The molecular pathogenesis of the myeloproliferative disorders (MPD) is poorly understood, except for chronic myeloid leukemia (CML). Recently, several groups have discovered a novel recurrent unique acquired clonal mutation in a tyrosine-kinase JAK2 in patients with Philadelphia-negative MPD and...
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