Article
Janus kinase 2 mutations in Philadelphia negative chronic myeloproliferative disorders: clinical implications.
Cancer letters - 18 Oct 2009
Panani Anna D
Abstract excerpt
The chronic myeloproliferative disorders (CMPD) are a group of clinically related diseases characterized by clonal hematopoiesis with increased proliferation of one or more myeloid cell lineages. The identification of JAK2 mutations (JAK2V617F and JAK2 exon 12) in patients with CMPD is of great significance in the understanding of the molecular mechanisms underlined the pathogenesis of the disease contributing...
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