Article
A test of Fisher's theory of dominance.
Proceedings of the National Academy of Sciences of the United States of America - 15 Dec 1991
Orr H A
Abstract excerpt
One of the first patterns noticed by geneticists was that mutations are almost always recessive to their wild-type alleles. Several explanations of this striking pattern have been offered. The two most influential are Fisher's theory--which argues that dominance results from natural selection against recurring deleterious mutations--and Wright's theory--which argues that dominance results from the physiology of...
Topics
- Alleles
- Animals
- Biological Evolution
- Chlamydomonas reinhardtii
- Chromosome Mapping
- Genes, Dominant
- Genes, Recessive
- Models, Genetic
- Mutation