Article
Fisher's historic 1922 paper On the dominance ratio.
Genetics - 3 Mar 2022
Charlesworth Brian
Abstract excerpt
R.A. Fisher's 1922 paper On the dominance ratio has a strong claim to be the foundation paper for modern population genetics. It greatly influenced subsequent work by Haldane and Wright, and contributed 3 major innovations to the study of evolution at the genetic level. First, the introduction of a general model of selection at a single locus, which showed how variability could be maintained by heterozygote...
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