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Article

Investigation of potential gene-gene interactions between APOE and RELN contributing to autism risk.

Psychiatric genetics - 1 Aug 2007

Ashley-Koch Allison E, Jaworski James, Ma De Qiong, Mei Hao, Ritchie Marylyn D, Skaar David A, Robert Delong G, Worley Gordon, Abramson Ruth K, Wright Harry H, Cuccaro Michael L, Gilbert John R, Martin Eden R, Pericak-Vance Margaret A

Abstract excerpt

BACKGROUND: Several candidate gene studies support RELN as susceptibility gene for autism. Given the complex inheritance pattern of autism, it is expected that gene-gene interactions will exist. A logical starting point for examining potential gene-gene interactions is to evaluate the joint effects of genes involved in a common biological pathway. RELN shares a common biological pathway with APOE, and Persico et...

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Source

Identifiers

PMID: 17621165
DOI: 10.1097/YPG.0b013e32809c2f75

Genes

RELN
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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