Article
The prevalence of factor V Leiden (G1691A), prothrombin G20210A and methylenetetrahydrofolate reductase C677T mutations in Jordanian patients with beta-thalassemia major.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Dec 2009
Al-Sweedan Suleimman A, Jaradat Said, Iraqi Muna, Beshtawi Mohamed
Abstract excerpt
One hundred beta-thalassemia major (beta-TM) patients and 100 individuals as control were included. Factor V Leiden and prothrombin G20210A and methylenetetrahydrofolate reductase (MTHFR) gene mutations were genotyped by PCR and allele-specific restriction enzyme techniques. The prevalence of factor V Leiden G1691A, MTHFR C677T and prothrombin G20210A in patients was insignificantly higher than controls. Patients...
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