Effect of Productive Human Papillomavirus 16 Infection on Global Gene Expression in Cervical Epithelium

Abstract excerpt

Persistent HPV infection is responsible for most cases of cervical cancer. The transition from precancerous to cancerous stages of HPV infection is marked by a significant reduction in virus production. Most global gene expression studies of HPV infection have focused on the cancerous stages. Therefore, little is known about global gene expression changes at precancerous stages. For the first time, we measured...

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