Article
Convergent Functional Genomics of bipolar disorder: from animal model pharmacogenomics to human genetics and biomarkers.
Neuroscience and biobehavioral reviews - 1 Jan 2007
Le-Niculescu H, McFarland M J, Mamidipalli S, Ogden C A, Kuczenski R, Kurian S M, Salomon D R, Tsuang Ming T, Nurnberger J I, Niculescu A B
Abstract excerpt
Progress in understanding the genetic and neurobiological basis of bipolar disorder(s) has come from both human studies and animal model studies. Until recently, the lack of concerted integration between the two approaches has been hindering the pace of discovery, or more exactly, constituted a missed opportunity to accelerate our understanding of this complex and heterogeneous group of disorders. Our group has...
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