Article
Phenotypic suppression methods for analyzing intra- and inter-molecular signaling interactions of chemoreceptors.
Methods in enzymology - 1 Jan 2007
Ames Peter, Parkinson John S
Abstract excerpt
The receptors that mediate chemotactic behaviors in E. coli and other motile bacteria and archaea are exquisite molecular machines. They detect minute concentration changes in the organism's chemical environment, integrate multiple stimulus inputs, and generate a highly amplified output signal that modulates the cell's locomotor pattern. Genetic dissection and suppression analyses have played an important role in...
Topics
- Agar
- Bacterial Proteins
- Biochemistry
- Chemoreceptor Cells
- Chemotaxis
- Escherichia coli
- Genotype
- Methylation
- Microbiological Techniques
- Models, Genetic
- Mutation
- Phenotype