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Article

Vertebrate DM domain proteins bind similar DNA sequences and can heterodimerize on DNA

1 Jan 2007

Abstract excerpt

BACKGROUND: The DM domain is a zinc finger-like DNA binding motif first identified in the sexual regulatory proteins Doublesex (DSX) and MAB-3, and is widely conserved among metazoans. DM domain proteins regulate sexual differentiation in at least three phyla and also control other aspects of development, including vertebrate segmentation. Most DM domain proteins share little similarity outside the DM domain. DSX...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 17605809
DOI: 10.1186/1471-2199-8-58

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