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Article

Transcriptional diversity of DMRT1 (dsx- and mab3-related transcription factor 1) in human testis.

Cell research - 1 Apr 2006

Cheng Han Hua, Ying Ming, Tian Yi Hao, Guo Yiqing, McElreavey Ken, Zhou Rong Jia

Abstract excerpt

Recent advances in the evolutionary genetics of sex determination indicate that the only molecular similarity in sex determination found so far among phyla is between the fly doublesex, worm mab-3 and vertebrate DMRT1(dsx- and mab3-related transcription factor 1) /DMY genes. Each of these factors encodes a zinc-finger-like DNA-binding motif, DM domain. Insights into the evolution and functions of human DMRT1 gene...

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Identifiers

PMID: 16617334
DOI: 10.1038/sj.cr.7310050

Genes

DMRT1

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Related research

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Transcriptional diversity of DMRT1 (dsx- and mab3-related transcription factor 1) in human testis.PMID 16617334Read ↗

DMRT1: An Ancient Sexual Regulator Required for Human GonadogenesisSemantic proximity Read ↗

Evolutionary dynamics of the DM domain gene family in metazoans.Semantic proximity Read ↗

Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testisSemantic proximity Read ↗

Vertebrate DM domain proteins bind similar DNA sequences and can heterodimerize on DNASemantic proximity Read ↗

Evidence for evolutionary conservation of sex-determining genes.Semantic proximity Read ↗

Dmrt1 is required for primary male sexual differentiation in Chinese soft-shelled turtle Pelodiscus sinensisSemantic proximity Read ↗

Zebrafish dmrta2 regulates the expression of cdkn2c in spermatogenesis in the adult testis.Semantic proximity Read ↗

Sex determination: the power of DMRT1.Semantic proximity Read ↗

The Dmrt1 expression in sex-reversed gonads of amphibiansSemantic proximity Read ↗

Sexual cell-fate reprogramming in the ovary by DMRT1.Semantic proximity Read ↗

Nuclear localization, DNA binding and restricted expression in neural and germ cells of zebrafish <i>Dmrt3</i>Semantic proximity Read ↗

The genomic structure of the highly-conserved dmrt1 gene in Solea senegalensis (Kaup, 1868) shows an unexpected intragenic duplication.Semantic proximity Read ↗

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