Article
Letermovir successfully used for secondary prophylaxis in a heart transplant recipient with ganciclovir-resistant cytomegalovirus syndrome (UL97 mutation).
Transplant infectious disease : an official journal of the Transplantation Society - 1 Oct 2018
Chong Pearlie P, Teiber Dagny, Prokesch Bonnie C, Arasaratnam Reuben J, Peltz Matthias, Drazner Mark H, Garg Sonia
Abstract excerpt
Letermovir was approved by the Food and Drug Administration (FDA) in November 2017 for use in adult cytomegalovirus (CMV)-seropositive allogeneic stem cell transplant (SCT) recipients for primary prophylaxis of CMV infection and disease. We report off-label use of letermovir for secondary prophylaxis of genotype-confirmed ganciclovir-resistant cytomegalovirus (CMV) syndrome (UL 97 mutation [C603W]) in a heart...
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