Article
Identification and characterization of equine granzyme B.
Veterinary immunology and immunopathology - 15 Aug 2007
Piuko Konrad, Bravo Ignacio G, Müller Martin
Abstract excerpt
In the present study we describe the isolation and characterization of putative equine granzyme B for which we propose the designation 'eqGrzmB'. Sequence analysis revealed characteristic features of a GrzmB protease such as the presence of a signal (leader-) peptide and an activation di-peptide. The isolated eqGrzmB is functionally active when expressed in human or in insect cells. Furthermore, exchange of any...
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