Article
Physiogenomic association of statin-related myalgia to serotonin receptors.
Muscle & nerve - 1 Sept 2007
Ruaño Gualberto, Thompson Paul D, Windemuth Andreas, Seip Richard L, Dande Amit, Sorokin Alexey, Kocherla Mohan, Smith Andrew, Holford Theodore R, Wu Alan H B
Abstract excerpt
We employed physiogenomic analyses to investigate the relationship between myalgia and selected polymorphisms in serotonergic genes, based on their involvement with pain perception and transduction of nociceptive stimuli. We screened 195 hypercholesterolemic, statin-treated patients, all of whom...
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