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Article

Partial rescue of glomerular laminin alpha5 mutations by wild-type endothelia produce hybrid glomeruli.

Journal of the American Society of Nephrology : JASN - 1 Aug 2007

Abrahamson Dale R, St John Patricia L, Isom Kathryn, Robert Barry, Miner Jeffrey H

Abstract excerpt

Both endothelial cells and podocytes are sources for laminin alpha1 at the inception of glomerulogenesis and then for laminin alpha5 during glomerular maturation. Why glomerular basement membranes (GBM) undergo laminin transitions is unknown, but this may dictate glomerular morphogenesis. In mice...

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Identifiers

PMID: 17599968
DOI: 10.1681/ASN.2007020207

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17599968-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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