Article
A dopamine D4 receptor exon 3 VNTR allele protecting against migraine without aura.
Annals of neurology - 1 Jun 2007
de Sousa Sara Campos, Karwautz Andreas, Wöber Christian, Wagner Gudrun, Breen Gerome, Zesch Heidi-Elisabeth, Konrad Andrea, Zormann Arno, Wanner Christian, Kienbacher Christian, Collier David A, Wöber-Bingöl Ciçek
Abstract excerpt
OBJECTIVE: As dopamine plays an important role in the pathophysiology of migraine and antimigraine drugs have an effect on the dopamine system, the objective of this study was to examine the dopamine D4 receptor gene for involvement in the cause of migraine. METHODS: We tested a VNTR-polymorphism in the dopamine D4 receptor gene, the exon 3 VNTR, in a sample of 190 family trios each with a proband with childhood...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
