Article
Sudden infant death syndrome: rare mutation in the serotonin system FEV gene.
Pediatric research - 1 Aug 2007
Rand Casey M, Berry-Kravis Elizabeth M, Zhou Lili, Fan Wenqing, Weese-Mayer Debra E
Abstract excerpt
Recent studies have identified abnormalities in the development and function of medullary serotonin (5-HT) pathways in postmortem brain from sudden infant death syndrome (SIDS) cases, suggesting 5-HT-mediated dysregulation of the autonomic nervous system (ANS) in SIDS. The human fifth Ewing variant (FEV) gene is specifically expressed in central 5-HT neurons in the brain, with a predicted role in specification...
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