Article
High serum serotonin in sudden infant death syndrome.
Proceedings of the National Academy of Sciences of the United States of America - 18 Jul 2017
Haynes Robin L, Frelinger Andrew L, Giles Emma K, Goldstein Richard D, Tran Hoa, Kozakewich Harry P, Haas Elisabeth A, Gerrits Anja J, Mena Othon J, Trachtenberg Felicia L, Paterson David S, Berry Gerard T, Adeli Khosrow, Kinney Hannah C, Michelson Alan D
Abstract excerpt
Sudden infant death syndrome (SIDS), the leading cause of postneonatal infant mortality, likely comprises heterogeneous disorders with the common phenotype of sudden death without explanation upon postmortem investigation. Previously, we reported that ∼40% of SIDS deaths are associated with abnormalities in serotonin (5-hydroxytryptamine, 5-HT) in regions of the brainstem critical in homeostatic regulation. Here...
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