Article
High prevalence of BRCA1 deletions in BRCAPRO-positive patients with high carrier probability.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Jun 2007
Veschi S, Aceto G, Scioletti A P, Gatta V, Palka G, Cama A, Mariani-Costantini R, Battista P, Calò V, Barbera F, Bazan V, Russo A, Stuppia L
Abstract excerpt
Mutation screening of the BRCA1 and BRCA2 genes in probands with familial breast/ovarian cancer has been greatly improved by the multiplex ligation-dependent probe amplification (MLPA) assay able to evidence gene rearrangements not detectable by standard screening methods. However, no criteria for selection of cases to be submitted to the MLPA test have been reported yet. We used the BRCAPro software for the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.