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Escherichia�coli ?-haemolysin induces focal leaks in colonic epithelium: a novel mechanism of bacterial translocation

25 Jun 2007

Abstract excerpt

Extraintestinal pathogenic Escherichia coli (ExPEC) are usually harmless colonizer of the intestinal microflora. However, they are capable to translocate and cause life-threatening disease. Translocation of ExPEC isolates was quantified in colonic monolayers. Transepithelial resistance (R(t)) was monitored and local changes in conductivity analysed with conductance scanning. Confocal microscopy visualized the...

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PMID: 17587334
DOI: 10.1111/j.1462-5822.2007.00978.x

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