Article
Changes in karyotype and azole susceptibility of sequential bloodstream isolates from patients with Candida glabrata candidemia.
Journal of clinical microbiology - 1 Aug 2007
Shin Jong Hee, Chae Myung Jong, Song Jeong Won, Jung Sook-In, Cho Duck, Kee Seung Jung, Kim Soo Hyun, Shin Myung Geun, Suh Soon Pal, Ryang Dong Wook
Abstract excerpt
We examined the changes in genotypes and azole susceptibilities among sequential bloodstream isolates of Candida glabrata during the course of fungemia and the relationship of these changes to antifungal therapy. Forty-one isolates were obtained from 15 patients (9 patients who received antifungal therapy and 6 patients who did not) over periods of up to 36 days. The isolates were analyzed using pulsed-field gel...
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