Article
Testing for gene x environment interaction effects in attention deficit hyperactivity disorder and associated antisocial behavior.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2008
Langley K, Turic D, Rice F, Holmans P, van den Bree M B M, Craddock N, Kent L, Owen M J, O'Donovan M C, Thapar A
Abstract excerpt
Gene x environment (G x E) interactions are increasingly thought to have substantial influence on the aetiology and clinical manifestations of complex disorders. In ADHD, although main effects of specific genetic variants and pre- or peri-natal variables have been reported and replicated using pooled analyses, few studies have looked at possible interactions. In a clinical sample of 266 children with ADHD, we...
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