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Article

The dopamine receptor D4 gene (DRD4) moderates family environmental effects on ADHD.

Journal of abnormal child psychology - 1 Jan 2011

Martel Michelle M, Nikolas Molly, Jernigan Katherine, Friderici Karen, Waldman Irwin, Nigg Joel T

Abstract excerpt

Attention-Deficit/Hyperactivity Disorder (ADHD) is a prime candidate for exploration of gene-by-environment interaction (i.e., G x E), particularly in relation to dopamine system genes, due to strong evidence that dopamine systems are dysregulated in the disorder. Using a G x E design, we examined whether the DRD4 promoter 120-bp tandem repeat polymorphism, previously associated with ADHD, moderated the effects...

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Share to Attention Deficit and Disruptive Behavior Disorders
Share to Attention Deficit Disorder with Hyperactivity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homozygote

Share to Parenting

Share to Promoter Regions, Genetic

Share to Receptors, Dopamine D4

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Source

Open in PubMed Open full text

Identifiers

PMID: 20644990
DOI: 10.1007/s10802-010-9439-5
PMCID: PMC4306231

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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