Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Crystal structure of Saccharomyces cerevisiae 6-phosphogluconate dehydrogenase Gnd1.

BMC structural biology - 14 Jun 2007

He Weiwei, Wang Yi, Liu Wei, Zhou Cong-Zhao

Abstract excerpt

BACKGROUND: As the third enzyme of the pentose phosphate pathway, 6-phosphogluconate dehydrogenase (6PGDH) is the main generator of cellular NADPH. Both thioredoxin reductase and glutathione reductase require NADPH as the electron donor to reduce oxidized thioredoxin or glutathione (GSSG). Since thioredoxin and GSH are important antioxidants, it is not surprising that 6PGDH plays a critical role in protecting...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Citric Acid
Share to Conserved Sequence
Share to Crystallography, X-Ray

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Deletion

Share to Phosphogluconate Dehydrogenase

Share to Protein Structure, Quaternary

Share to Saccharomyces cerevisiae

Share to Sequence Alignment

Source

Open in PubMed Open full text

Identifiers

PMID: 17570834
DOI: 10.1186/1472-6807-7-38
PMCID: PMC1919378

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Crystal structure of Saccharomyces cerevisiae 6-phosphogluconate dehydrogenase Gnd1.PMID 17570834Read ↗

Allosteric role of a structural NADP+ molecule in glucose-6-phosphate dehydrogenase activity.Semantic proximity Read ↗

Human glucose-6-phosphate dehydrogenase: the crystal structure reveals a structural NADP(+) molecule and provides insights into enzyme deficiency.Semantic proximity Read ↗

Identification of the first fungal NADP-GAPDH from Kluyveromyces lactis.Semantic proximity Read ↗

Structural studies of glucose-6-phosphate and NADP+ binding to human glucose-6-phosphate dehydrogenase.Semantic proximity Read ↗

Lysine245 plays a crucial role in stability and function of glycerol 3-phosphate dehydrogenase (Gpd1) in Saccharomyces cerevisiae.Semantic proximity Read ↗

Cloning and characterization of CmGPD1, the Candida magnoliae homologue of glycerol-3-phosphate dehydrogenase.Semantic proximity Read ↗

Genome-wide transcriptional response of a Saccharomyces cerevisiae strain with an altered redox metabolism.Semantic proximity Read ↗

Three-dimensional modeling of glucose-6-phosphate dehydrogenase-deficient variants from German ancestry.Semantic proximity Read ↗

Intracellular NADPH levels affect the oligomeric state of the glucose 6-phosphate dehydrogenase.Semantic proximity Read ↗

Leishmania mexicana glycerol-3-phosphate dehydrogenase showed conformational changes upon binding a bi-substrate adduct.Semantic proximity Read ↗

SUGAR-DEPENDENT6 encodes a mitochondrial flavin adenine dinucleotide-dependent glycerol-3-p dehydrogenase, which is required for glycerol catabolism and post germinative seedling growth in Arabidopsis.Semantic proximity Read ↗

A gene encoding sn-glycerol 3-phosphate dehydrogenase (NAD+) complements an osmosensitive mutant of Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.