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Article

Genetic prediction of future type 2 diabetes.

PLoS medicine - 1 Nov 2005

Lyssenko Valeriya, Almgren Peter, Anevski Dragi, Orho-Melander Marju, Sjögren Marketa, Saloranta Carola, Tuomi Tiinamaija, Groop Leif

Abstract excerpt

BACKGROUND: Type 2 diabetes (T2D) is a multifactorial disease in which environmental triggers interact with genetic variants in the predisposition to the disease. A number of common variants have been associated with T2D but our knowledge of their ability to predict T2D prospectively is limited. METHODS AND FINDINGS: By using a Cox proportional hazard model, common variants in the PPARG (P12A), CAPN10 (SNP43 and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17570749
DOI: 10.1371/journal.pmed.0020345
PMCID: PMC1274281

Genes

CAPN10
PPARG
IRS1
KCNJ11
UCP2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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