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Article

Canalization of segmentation and its evolution in Drosophila.

Proceedings of the National Academy of Sciences of the United States of America - 26 Jun 2007

Lott Susan E, Kreitman Martin, Palsson Arnar, Alekseeva Elena, Ludwig Michael Z

Abstract excerpt

Segmentation in Drosophila embryogenesis occurs through a hierarchical cascade of regulatory gene expression driven by the establishment of a diffusion-mediated morphogen gradient. Here, we investigate the response of this pattern formation process to genetic variation and evolution in egg size. Specifically, we ask whether spatial localization of gap genes Kruppel (Kr) and giant (gt) and the pair-rule gene...

Topics

Animals
Biological Evolution
Body Patterning
Drosophila
Drosophila melanogaster
Embryonic Development
Genetic Variation
Ovum
Species Specificity

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17569783
DOI: 10.1073/pnas.0701359104
PMCID: PMC1891814

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