Article
Ovarian gene expression in the absence of FIGLA, an oocyte-specific transcription factor
13 Jun 2007
Abstract excerpt
BACKGROUND: Ovarian folliculogenesis in mammals is a complex process involving interactions between germ and somatic cells. Carefully orchestrated expression of transcription factors, cell adhesion molecules and growth factors are required for success. We have identified a germ-cell specific, basic helix-loop-helix transcription factor, FIGLA (Factor In the GermLine, Alpha) and demonstrated its involvement in two...
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