Article
Isozyme polymorphisms in human diploid cell strains for research on cellular aging.
Experimental gerontology - 1 Jan 1991
Tasaki Y, Ohara T, Yamamoto M, Yamamoto K
Abstract excerpt
Six human lung diploid cell strains established for the study of in vitro cellular aging (TIG-1, TIG-7, WI-38, IMR-90, MRC-5, MRC-9, and HeLa cells as a control) were studied by cellulose acetate membrane electrophoresis for allozymic differences at 18 enzyme loci. Eight enzyme loci (G6PD, PGM1, PGM3, PepA, PGD, ADA, GLO1, and ME), proved to be informative in establishing unique allozyme genetic signatures for...
Topics
- Cell Line
- Cell Physiological Phenomena
- Cells
- Cellular Senescence
- Electrophoresis, Cellulose Acetate
- Fibroblasts
- Humans
- Isoenzymes
- Lung
- Phenotype
- Ploidies
- Polymorphism, Genetic