Article
Automated comparative sequence analysis by base-specific cleavage and mass spectrometry for nucleic acid-based microbial typing.
Proceedings of the National Academy of Sciences of the United States of America - 19 Jun 2007
Honisch Christiane, Chen Yong, Mortimer Chloe, Arnold Catherine, Schmidt Oliver, van den Boom Dirk, Cantor Charles R, Shah Haroun N, Gharbia Saheer E
Abstract excerpt
Traditional microbial typing technologies for the characterization of pathogenic microorganisms and monitoring of their global spread are often difficult to standardize and poorly portable, and they lack sufficient ease of use, throughput, and automation. To overcome these problems, we introduce the use of comparative sequencing by MALDI-TOF MS for automated high-throughput microbial DNA sequence analysis. Data...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.