Article
Genetic polymorphism of TLR4 gene and correlation with mastitis in cattle.
Journal of genetics and genomics = Yi chuan xue bao - 1 May 2007
Wang Xingping, Xu Shangzhong, Gao Xue, Ren Hongyan, Chen Jinbao
Abstract excerpt
Toll-like receptor 4 (TLR4) recognizes pathogen ligands and mediates signaling to initiate innate and adaptive immune responses. In this experiment, a 316 bp and 382 bp fragments of TLR4 gene named T4CRBR1 and T4CRBR2, of Chinese Holstein, Sanhe cattle, and Chinese Simmental was amplified by polymerase chain reaction (PCR), respectively. The genetic polymorphisms in the three populations were detected by...
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