Article
Molecular characterization of CRBR2 fragment of TLR4 gene in association with mastitis in Vrindavani cattle.
Microbial pathogenesis - 1 Apr 2022
Panigrahi Manjit, Kumar Harshit, Nayak Sonali Sonejita, Rajawat Divya, Parida Subhashree, Bhushan Bharat, Sharma Arjava, Dutt Triveni
Abstract excerpt
The bovine TLR4 gene is an interesting candidate marker for mastitis resistance, since it is involved in neutrophil migration to and from the mammary gland during mastitis. TLR4 detects pathogen ligands, such as the Escherichia coli lipopolysaccharide (LPS) endotoxin and facilitates innate and adaptive immune responses. In the current study, a total of 130 crossbred cows (74 mastitis tolerant and 56 with clinical...
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