Article
Toll-like receptor 2 gene polymorphism and its relationship with SCS in dairy cattle.
Animal biotechnology - 1 Jan 2009
Zhang L P, Gan Q F, Ma T H, Li H D, Wang X P, Li J Y, Gao X, Chen J B, Ren H Y, Xu S Z
Abstract excerpt
Toll-like receptor 2 (TLR2) plays an important role in the innate immune response to a variety of pathogens. In this study, bovine TLR2 gene was taken as a candidate gene for mastitis resistance. Through PCR-SSCP analysis and sequencing, three missense mutations at T385 G, G398A, and G1884A were detected in the coding region that encoded extracellular domain. Altogether 240 dairy cattle of three breeds (Holstein,...
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