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Article

Immunologic and molecular mechanisms in inflammatory bowel disease.

The Surgical clinics of North America - 1 Jun 2007

Ince M Nedim, Elliott David E

Abstract excerpt

Molecular and immunologic mechanisms underlying inflammation in inflammatory bowel disease (IBD) are largely unknown. Recent studies have helped better characterize genetic and environmental factors associated with colitis. Discoveries of genetic variants have confirmed that IBD is a bacteria and cytokine-driven pathologic immune response. Data have demonstrated that certain T cell subsets are important in...

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PMID: 17560420
DOI: 10.1016/j.suc.2007.03.005

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