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Article

The GNB3 C825T polymorphism affects response to HCV therapy with pegylated interferon in HCV/HIV co-infected but not in HCV mono-infected patients.

Journal of hepatology - 1 Sept 2007

Ahlenstiel Golo, Nischalke Hans Dieter, Bueren Karin, Berg Thomas, Vogel Martin, Biermer Michael, Grünhage Frank, Sauerbruch Tilman, Rockstroh Jürgen, Spengler Ulrich, Nattermann Jacob

Abstract excerpt

BACKGROUND/AIMS: Response to HCV treatment with pegylated interferon-alpha is variable but might at least in part depend on genetic host factors. The G protein beta3 unit (GNB3) C825T polymorphism has been shown to affect treatment response in HCV mono-infection. Here, we analyzed the impact of the GNB3 genotype in the context of HCV/HIV co-infection. METHODS: HIV/HCV co-infected (n=112) and HCV mono-infected...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17559964
DOI: 10.1016/j.jhep.2007.04.008

Genes

GNB3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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