Article
The oncogenic potential of human papillomaviruses: a review on the role of host genetics and environmental cofactors.
The British journal of dermatology - 1 Aug 2007
Madkan V K, Cook-Norris R H, Steadman M C, Arora A, Mendoza N, Tyring S K
Abstract excerpt
Human papillomaviruses (HPVs), with over 100 genotypes, are a very complex group of human pathogenic viruses. In most cases, HPV infection results in benign epithelial proliferations (verrucae). However, oncogenic types of HPV may induce malignant transformation in the presence of cofactors. For example, over 99% of all cervical cancers and a majority of vulval, vaginal, anal and penile cancers are the result of...
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