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Article

Phenotypic and functional effects of heat shock protein 90 inhibition on dendritic cell.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2007

Bae Jooeun, Mitsiades Constantine, Tai Yu-Tzu, Bertheau Robert, Shammas Masood, Batchu Ramesh Babu, Li Cheng, Catley Lawrence, Prabhala Rao, Anderson Kenneth C, Munshi Nikhil C

Abstract excerpt

The 90-kDa heat shock protein (Hsp90) plays an important role in conformational regulation of cellular proteins and thereby cellular signaling and function. As Hsp90 is considered a key component of immune function and its inhibition has become an important target for cancer therapy, we here evaluated the role of Hsp90 in human dendritic cell (DC) phenotype and function. Hsp90 inhibition significantly decreased...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17548610
DOI: 10.4049/jimmunol.178.12.7730

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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