Article
A genome-wide Ras-effector interaction network.
Journal of molecular biology - 27 Jul 2007
Kiel Christina, Foglierini Mathilde, Kuemmerer Nico, Beltrao Pedro, Serrano Luis
Abstract excerpt
Here using structural information and protein design tools we have drawn the network of interactions between 20 Ras subfamily proteins with 50 putative Ras binding domains. To validate this network we have cloned six poorly characterized Ras binding domains (RBD) and two Ras proteins (RERG, DiRas...
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