Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ras history

1 Jul 2010

Abstract excerpt

Although the roots of Ras sprouted from the rich history of retrovirus research, it was the discovery of mutationally activated RAS genes in human cancer in 1982 that stimulated an intensive research effort to understand Ras protein structure, biochemistry and biology. While the ultimate goal has been developing anti-Ras drugs for cancer treatment, discoveries from Ras have laid the foundation for three broad...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Protein Kinase Regulation and GTPase Signaling
Share to Protein Tyrosine Phosphatases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21686117
DOI: 10.4161/sgtp.1.1.12178

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ras historyPMID 21686117Read ↗

A brief history of RAS and the RAS Initiative.Semantic proximity Read ↗

The Ras superfamily at a glanceSemantic proximity Read ↗

40 Years of RAS—A Historic OverviewSemantic proximity Read ↗

Ras oncogenes and their downstream targets.Semantic proximity Read ↗

The RAS subfamily Evolution – tracing evolution for its utmost exploitationSemantic proximity Read ↗

RAS Proteins and Their Regulators in Human Disease.Semantic proximity Read ↗

RAS: Striking at the Core of the Oncogenic CircuitrySemantic proximity Read ↗

A thirty-year quest for a role of R-Ras in cancer: from an oncogene to a multitasking GTPase.Semantic proximity Read ↗

Biology, pathology, and therapeutic targeting of RAS.Semantic proximity Read ↗

RAS: Circuitry and therapeutic targeting.Semantic proximity Read ↗

The molecular genetics of RASopathies : An update on novel disease genes and new disordersSemantic proximity Read ↗

The Ins and Outs of RAS Effector Complexes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.