Cytogenetic aberrations in neuropathy associated with IgM monoclonal gammopathy.

doi:10.1016/j.jns.2007.04.022

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Article

Cytogenetic aberrations in neuropathy associated with IgM monoclonal gammopathy.

Journal of the neurological sciences - 15 Sept 2007

Eurelings Marijke, Lokhorst Henk M, Notermans Nicolette C, Krijtenburg Pieter Jaap, Kessel Berris van, Eleveld Mark J, Bloem Andries, Wokke John H, Poot Martin, Buijs Arjan

Abstract excerpt

The occurrence and nature of cytogenetic aberrations in polyneuropathy associated with IgM monoclonal gammopathy was determined. Therefore, interphase fluorescence in situ hybridization (FISH) was applied in 22 patients with polyneuropathy associated with IgM monoclonal gammopathy, multiplex ligation-dependent probe amplification (MLPA) assay in 18 of these patients and genome-wide-array-based comparative genomic...

Topics

Aged
B-Lymphocytes
Chromosome Aberrations
Chromosomes, Human, Pair 14
DNA Mutational Analysis
Female
Genetic Predisposition to Disease
Genetic Testing
Genotype
Humans
Immunoglobulin M
In Situ Hybridization, Fluorescence

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Paraproteinemias

Peripheral Nerves

Polyneuropathies

Waldenstrom Macroglobulinemia

Source

Open in PubMed

Identifiers

PMID: 17543994
DOI: 10.1016/j.jns.2007.04.022

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