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Article

The regulation of zinc homeostasis by the ZafA transcriptional activator is essential for Aspergillus fumigatus virulence.

Molecular microbiology - 1 Jun 2007

Moreno Miguel Angel, Ibrahim-Granet Oumaima, Vicentefranqueira Rocío, Amich Jorge, Ave Patrick, Leal Fernando, Latgé Jean-Paul, Calera José Antonio

Abstract excerpt

We have previously shown that Aspergillus fumigatus is able to grow in zinc-limiting media and that this ability is regulated at transcriptional level by both the availability of zinc and pH. When A. fumigatus grows as a pathogen, it must necessarily obtain zinc from the zinc-limiting environment provided by host tissue. Accordingly, the regulation of zinc homeostasis by some zinc-responsive transcriptional...

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PMID: 17542914
DOI: 10.1111/j.1365-2958.2007.05726.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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