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Article

Constitutive deficiency in DNA mismatch repair: is it time for Lynch III?

Clinical genetics - 1 Jun 2007

Felton K E A, Gilchrist D M, Andrew S E

Abstract excerpt

Hereditary non-polyposis colorectal cancer (HNPCC), also known as Lynch syndrome types I and II, and the related subtypes Turcot and Muir-Torre syndrome, have all been associated with inheritance of germ line mutations in the DNA mismatch repair (MMR) genes. Fifty individuals have recently been identified with an early onset of a different spectrum of cancers associated with inheritance of two MMR...

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Identifiers

PMID: 17539898
DOI: 10.1111/j.1399-0004.2007.00801.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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