Article
A mutation on influenza C virus M1 protein affects virion morphology by altering the membrane affinity of the protein.
Journal of virology - 1 Aug 2007
Muraki Yasushi, Murata Toshio, Takashita Emi, Matsuzaki Yoko, Sugawara Kanetsu, Hongo Seiji
Abstract excerpt
Reverse genetics has been documented for influenza A, B, and Thogoto viruses belonging to the family Orthomyxoviridae. We report here the reverse genetics of influenza C virus, another member of this family. The seven viral RNA (vRNA) segments of C/Ann Arbor/1/50 were expressed in 293T cells from cloned cDNAs, together with nine influenza C virus proteins. At 48 h posttransfection, the infectious titer of the...
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