Article
Direct selection of RNA beacon aptamers.
Biochemical and biophysical research communications - 20 Jul 2007
Morse Daniel P
Abstract excerpt
A method for the direct selection of RNA molecules that can be easily converted into beacon aptamers is presented. Beacon aptamers are fluorescently labeled nucleic acids that signal the presence of a specific ligand through changes in fluorescence intensity. Typically, ligand binding causes an increase in fluorescence intensity by inducing a conformational change that separates a fluorophore/quencher pair. The...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
