Article
microMRI-HREM pipeline for high-throughput, high-resolution phenotyping of murine embryos.
Journal of anatomy - 1 Jul 2007
Pieles Guido, Geyer Stefan H, Szumska Dorota, Schneider Jürgen, Neubauer Stefan, Clarke Kieran, Dorfmeister Karl, Franklyn Angela, Brown Steve D, Bhattacharya Shoumo, Weninger Wolfgang J
Abstract excerpt
Rapid and precise phenotyping analysis of large numbers of wild-type and mutant mouse embryos is essential for characterizing the genetic and epigenetic factors regulating embryogenesis. We present a novel methodology that permits precise high-throughput screening of the phenotype of embryos with both targeted and randomly generated mutations. To demonstrate the potential of this methodology we show embryo...
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