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Article

The disulfide loop of gp41 is critical to the furin recognition site of HIV gp160.

Protein science : a publication of the Protein Society - 1 Jun 2007

Sen Jayita, Jacobs Amy, Jiang Haiqing, Rong Lijun, Caffrey Michael

Abstract excerpt

The importance of the HIV gp41 conserved disulfide loop to envelope function has been examined by mutational and functional analyses. Based on a luciferase-reporter entry assay, mutants gp41-CC/AA (C598A/C604A) and gp41-Delta (deletion of residues 596-606) result in a nonfunctional envelope prote...

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Identifiers

PMID: 17525470
DOI: 10.1110/ps.072771407
PMCID: PMC2206660

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17525470-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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