Article
Computational characterization of structural role of the non-active site mutation M36I of human immunodeficiency virus type 1 protease.
Journal of molecular biology - 13 Jul 2007
Ode Hirotaka, Matsuyama Shou, Hata Masayuki, Neya Saburo, Kakizawa Junko, Sugiura Wataru, Hoshino Tyuji
Abstract excerpt
A prominent characteristic of human immunodeficiency virus type 1 (HIV-1) is its high genetic variability, which generates diversity of the virus and often causes a serious problem of the emergence of drug-resistant mutants. Subtype B HIV-1 is dominant in advanced countries, and the mortality rat...
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