Article
Three-locus systems impose additional constraints on pairwise disequilibria.
Genetics - 1 Nov 1991
Robinson W P, Asmussen M A, Thomson G
Abstract excerpt
Combinations of allele frequencies and pairwise linkage disequilibrium terms, each of which is permissible at the two-locus level, may not always be permissible at the three-locus level. These additional constraints on the possible maximum and minimum values for the pairwise disequilibrium terms are formally determined and numerically analyzed. In some cases, the three-locus constraints on a pairwise...
Topics
- Alleles
- Gene Frequency
- Genetic Linkage
- Genetics, Population
- Haplotypes
- Mathematics
- Models, Theoretical