Monozygous twins with a microdeletion syndrome involving BTK, DDP1, and two other genes; evidence of intact dendritic cell development and TLR responses.

doi:10.1007/s00431-007-0493-0

Article

Monozygous twins with a microdeletion syndrome involving BTK, DDP1, and two other genes; evidence of intact dendritic cell development and TLR responses.

European journal of pediatrics - 1 Mar 2008

Jyonouchi Harumi, Geng Lee, Törüner Gökçe A, Vinekar Kavita, Feng Di, Fitzgerald-Bocarsly Patricia

Abstract excerpt

UNLABELLED: We report for the first time monozygous twins with a microdeletion syndrome involving genes coding for Bruton's tyrosine kinase (Btk) and deafness-dystonia peptide 1 (DDP1), and two other genes. Apart from its essential role in B cell development, Btk is indicated to affect signaling mediated by toll like receptors (TLRs) and development of dendritic cells (DCs) but results are conflictive. The twins...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Monozygous twins with a microdeletion syndrome involving BTK, DDP1, and two other genes; evidence of intact dendritic cell development and TLR responses.

Abstract excerpt

Topics

Related research